MétaCan
Menu
Back to cohort
Record W2047639980 · doi:10.1126/science.1240156

Ethics and Genomic Incidental Findings

2013· article· en· W2047639980 on OpenAlexaff
Amy L. McGuire, Steven Joffe, Barbara A. Koenig, Barbara B. Biesecker, Laurence B. McCullough, Jennifer S. Blumenthal‐Barby, Timothy Caulfield, Sharon F. Terry, Robert C. Green

Bibliographic record

VenueScience · 2013
Typearticle
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsUniversity of Alberta
FundersNational Cancer InstituteNational Human Genome Research InstituteNational Institutes of Health
KeywordsObligationPsychologyMedicineComputational biologyBiologyPolitical scienceLaw

Abstract

fetched live from OpenAlex

Laboratories have an obligation to report clinically beneficial incidental findings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.120
metaresearch head score (Gemma)0.246
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.120
Threshold uncertainty score0.637

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1200.246
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0060.047
Scholarly communication0.0070.005
Open science0.0020.007
Research integrity0.0190.013
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.458
GPT teacher head0.593
Teacher spread0.136 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations171
Published2013
Admission routes1
Has abstractyes

Explore more

Same venueScienceSame topicEthics in Clinical ResearchFrench-language works237,207