Rapid Morphological Reorganization of the Rabbit Corneal Endothelium after Acute Exposure to Sodium Lactate in vitro
Bibliographic record
Abstract
Corneal stroma-endothelial preparations from 2-kg albino rabbits were incubated in vitro in a bicarbonate-Ringer solution equilibrated with 5% CO2-9% O2 over 4 h in half-chambers at 37 degrees C. An average net fluid pump activity of 6.8 microliters/h was measured in the 4th hour. If such preparations were initially equilibrated with bicarbonate-Ringer for 90 min and then challenged for 20 min with 15 mM sodium lactate or NaCl, an osmotically induced increase in fluid flow occurred. After removal of the challenge and return to bicarbonate-Ringer for 2.5 h, the net fluid pump returned to baseline and then increased again (to an average of 9.7 microliters/h) for the lactate- but not NaCl-challenged endothelia. Scanning electron microscopy showed that lactate-challenged (but not the control or NaCl-challenged) endothelial contained a moderate number of very large pleomorphic cells within an otherwise regular mosaic. It is proposed that the large cells develop as a result of cell fusion (coalescence).
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".