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Record W2049372139 · doi:10.1097/ede.0b013e318276c005

Long-Term Exposure to Traffic-Related Air Pollution and Cardiovascular Mortality

2012· article· en· W2049372139 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueEpidemiology · 2012
Typearticle
Languageen
FieldEnvironmental Science
TopicAir Quality and Health Impacts
Canadian institutionsHealth CanadaMcGill University Health CentreMcGill UniversityUniversity of TorontoPublic Health Ontario
FundersCanadian Institutes of Health Research
KeywordsMedicineHazard ratioConfidence intervalDemographyProportional hazards modelCohortEnvironmental healthRelative riskCohort studyAir pollutionInternal medicine

Abstract

fetched live from OpenAlex

BACKGROUND: Findings from previous cohort studies suggest a positive association between traffic-related air pollution and cardiovascular mortality. However, few studies have assessed intraurban variation in traffic-related pollution or evaluated cardiovascular effects at lower levels of pollution that are typically seen in Canadian cities. METHODS: We conducted a cohort study of traffic-related air pollution and cardiovascular mortality among adults who lived in three cities in Ontario, Canada. Study members of the cohort were a random sample from the federal family income tax database, comprising 205,440 adults age 35-85 years, who lived in Toronto, Hamilton, or Windsor between 1982 and 1986. Follow-up ended on 31 December 2004. Mortality from cardiovascular and cerebrovascular diseases was ascertained using the Canadian Mortality Database. We estimated time-dependent concentrations of ambient nitrogen dioxide (NO2) from land-use regression models and assigned exposures to residences of subjects. Rate ratios (RRs) were estimated from Cox proportional hazard model adjusted for individual risk factors and selected contextual covariables. We adjusted indirectly for smoking and obesity. RESULTS: The spatial distributions of NO2 did not change appreciably over the follow-up period. Cumulative exposure to NO2 was associated with a 12% increase in mortality from cardiovascular disease for each increase of 5 parts per billion of NO2 (95% confidence interval [CI] = 7%-17%) and a 15% increase (8%-21%) in mortality from ischemic heart disease. Risks of cardiovascular mortality were also increased with shorter term exposures, but the RRs were somewhat smaller. No association was found for cerebrovascular mortality (RR = 0.99 [95% CI = 0.91-1.08]). CONCLUSION: Traffic-related air pollution at relatively low concentrations in Ontario was associated with increased mortality from cardiovascular disease.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.038
Threshold uncertainty score0.691

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.084
GPT teacher head0.350
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it