MétaCan
Menu
Back to cohort
Record W2049921021 · doi:10.1002/prot.21297

NMR structure of protein yjbR from <i>Escherichia coli</i> reveals ‘double‐wing’ DNA binding motif

2007· article· en· W2049921021 on OpenAlexaff
Kiran Kumar Singarapu, Gaohua Liu, Rong Xiao, Claudia Bertonati, Barry Honig, G.T. Montelione, Thomas Szyperski

Bibliographic record

VenueProteins Structure Function and Bioinformatics · 2007
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRNA and protein synthesis mechanisms
Canadian institutionsStructural Genomics Consortium
FundersNational Institute of General Medical SciencesUniversity at BuffaloState University of New YorkNational Institutes of HealthNational Science Foundation
KeywordsMotif (music)DNAEscherichia coliChemistryBiochemistryArtGene

Abstract

fetched live from OpenAlex

Introduction.126-residue protein yjbR (gi|85674275, SwissProt/TrEMBL ID YJBR_ECOLI, access number P0AF50) encoded by gene YJBR_ECOLI from Escherichia coli has no significant sequence similarity with any protein with known three-dimensional structure.Protein yjbR was selected by the Protein Structure Initiave-2 of the United States National Institutes of Health and was assigned to the Northeast Structural Genomics Consortium (NESG; http://www.nesg.org)(NESG target ID ER226).Protein yjbR belongs to Protein Family (Pfam 1 ) PF04237 which contains 133 proteins.No functional annotations are so far available.Here we report the high-quality NMR solution structure of protein yjbR, which was determined by recently developed rapid NMR data collection and analysis protocol for high-throughput protein structure determination.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.212
Teacher spread0.204 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2007
Admission routes1
Has abstractyes

Explore more

Same venueProteins Structure Function and BioinformaticsSame topicRNA and protein synthesis mechanismsFrench-language works237,207