Molecular oxygen as a paramagnetic NMR probe of protein solvent exposure and topology
Why this work is in the frame
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Bibliographic record
Abstract
Abstract This review focuses on the applications of dissolved oxygen in NMR studies of protein topology. A brief discussion is given to explain the origin of O 2 ‐induced paramagnetic shifts and relaxation rate enhancements, which are seen for a variety of nuclei of biological interest—in particular 13 C, 19 F, and 1 H. We also give examples of applications of paramagnetic effects from dissolved O 2 , which include studies of solvent exposure, hydrophobicity, transient contacts or local clustering in intrinsically disordered proteins, immersion depth in membranous systems, and topology of membrane proteins. © 2008 Wiley Periodicals, Inc. Concepts Magn Reson Part A 32A: 239–253, 2008.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it