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A Randomized, Double-Blind Study of Paliperidone Extended-Release in Treatment of Acute Schizophrenia in Adolescents

2011· article· en· 100 citations· W2050493658 on OpenAlex· 10.1016/j.biopsych.2011.06.021

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Full frame distilled prediction

Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

Candidate categories
none
Consensus categories
none
Domain
Candidate signal: noneConsensus signal: none
Study design
Candidate signal: Randomized trialConsensus signal: Randomized trial
Genre
Candidate signal: EmpiricalConsensus signal: Empirical
Teacher disagreement score
0.076
Threshold uncertainty score
0.653
Validation status
machine_predicted_unvalidated · codex-gemma-dda1882f352a

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.092
GPT teacher head0.349
Teacher spread
0.257 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Biological Psychiatry
Topic
Schizophrenia research and treatment
Field
Medicine
Canadian institutions
not available
Funders
Forest PharmaceuticalsJanssen BiotechNational Institute of Child Health and Human DevelopmentBristol-Myers Squibb CanadaMerckNational Institute of Mental HealthSupernus PharmaceuticalsPfizer UK
Keywords
PaliperidoneSchizophrenia (object-oriented programming)Double blindPaliperidone PalmitateMedicineRandomized controlled trialPsychologyPsychiatryInternal medicineAntipsychoticPlacebo
Has abstract in OpenAlex
no