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Multiple sclerosis and delayed mumps

2009· article· en· W2050727112 on OpenAlexaffabout
Peter L. Hays

Bibliographic record

VenueActa Neurologica Scandinavica · 2009
Typearticle
Languageen
FieldMedicine
TopicVirology and Viral Diseases
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsMultiple sclerosisMedicinePediatricsImmunology

Abstract

fetched live from OpenAlex

To test the hypothesis that mumps occurs less frequently and later in patients with multiple sclerosis, histories were taken from patients and matched controls by a single observer at a university hospital in Canada, and in the course of domiciliary visits in England. 63 consecutive patients with multiple sclerosis in two neurological practices, and 63 controls matched for age, sex and childhood domicile, together with 29 sibs of English patients were studied. Patients had mumps at an older age (12.3:8.6, p less than 0.04) and less frequently (33/63 vs 60/92, p = 0.08). Multiple sclerosis patients display a partial immunity to mumps, of which the most obvious explanation is a preceding infection by an antigenically related paramyxovirus, that is, by either the Newcastle Disease virus, or parainfluenza.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.291
Threshold uncertainty score0.520

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.261
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2009
Admission routes2
Has abstractyes

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