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Record W2051856294 · doi:10.1186/1756-3305-2-7

Onchocerciasis Control: Vision for the Future from a Ghanian perspective

2009· article· en· W2051856294 on OpenAlexaff
Mark J. Taylor, Kwablah Awadzi, Marı́a-Gloria Basáñez, Nana‐Kwadwo Biritwum, Daniel A. Boakye, Boakye A. Boatin, Moses J. Bockarie, Thomas S. Churcher, Alexander Yaw Debrah, Geoffrey Edwards, Achim Hoerauf, Sabine Mand, G. A. Matthews, Mike Y. Osei‐Atweneboana, Roger K. Prichard, Samuel Wanji, Ohene Adjei

Bibliographic record

VenueParasites & Vectors · 2009
Typearticle
Languageen
FieldMedicine
TopicParasitic Diseases Research and Treatment
Canadian institutionsMcGill University
FundersRoyal SocietyBill and Melinda Gates Foundation
KeywordsOnchocerciasisIvermectinDonationResistance (ecology)Control (management)BiologyVeterinary medicineMedicineImmunologyPolitical scienceEcologyLawManagement

Abstract

fetched live from OpenAlex

Since 1987 onchocerciasis control has relied on the donation of ivermectin (Mectizan(R), Merck & Co., Inc.) through the Mectizan Donation Programme. Recently, concern has been raised over the appearance of suboptimal responses to ivermectin in Ghana - highlighting the potential threat of the development of resistance to ivermectin. This report summarises a meeting held in Ghana to set the research agenda for future onchocerciasis control. The aim of this workshop was to define the research priorities for alternative drug and treatment regimes and control strategies to treat populations with existing evidence of suboptimal responsiveness and define research priorities for future control strategies in the event of the development of widespread ivermectin resistance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.013
Threshold uncertainty score0.045

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0020.007
Scholarly communication0.0060.009
Open science0.0020.003
Research integrity0.0080.007
Insufficient payload (model declined to judge)0.0130.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.351
Teacher spread0.341 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations61
Published2009
Admission routes1
Has abstractyes

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