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Failure of PDE5 Inhibitor Use: A Case of Nonresponder? (CME)

2010· article· en· W2054845046 on OpenAlexaff
Eric Chung

Bibliographic record

VenueThe Journal of Sexual Medicine · 2010
Typearticle
Languageen
FieldMedicine
TopicSexual function and dysfunction studies
Canadian institutionsSt Joseph's Health Care
Fundersnot available
KeywordsMedicineFamily medicineLibrary scienceComputer science

Abstract

fetched live from OpenAlex

A 55-year-old married man presented to our service with a 3-year history of erectile dysfunction (ED). Prior to seeing us, he had obtained a prescription from his local general practitioner for four sildenafil (Viagra®) tablets (50 mg) and had found them to be ineffective. Subsequently, he also tried two tadalafil (Cialis®) tablets (20 mg) and vardenafil (Levitra ®[20 mg]) with no improvement in his erection function. His past medical history includes obesity (BMI 32), hypertension (on atenolol), active smoker (20 cigarettes per day) with a 40-pack year history and diabetes (diet-controlled). He reported that he is unable to achieve and maintain his erection in nearly all circumstances on all occasions with his wife, whom he describes as supportive. He denied previous penile trauma or any deformity, and believes that his erections have become progressively less rigid over the past 3 years. He denied any sensory changes on the shaft or glans. His sexual interest remains strong but even with self-stimulation he is unable to gain adequate rigidity, but reported that his ejaculation and orgasm remain intact.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.822
Threshold uncertainty score0.855

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.047
GPT teacher head0.329
Teacher spread0.282 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2010
Admission routes1
Has abstractyes

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