MétaCan
Menu
Back to cohort
Record W2054938157 · doi:10.1111/jvh.12247

Historical epidemiology of hepatitis C virus (<scp>HCV</scp>) in selected countries

2014· review· en· W2054938157 on OpenAlex
Philip Bruggmann, Thomas Berg, Anne Øvrehus, Christophe Moreno, Carlos Eduardo Brandão‐Mello, Françoise Roudot‐Thoraval, Rui Tato Marinho, Morris Sherman, Stephen Ryder, Jan Šperl, Ulus Salih Akarca, İsmail Balık, Florian Bihl, Marc Bilodeau, Antonio Javier Blasco, Marı́a Buti, Filipe Calinas, José Luís Calleja, Hugo Cheinquer, Peer Brehm Christensen, Mette Rye Clausen, Henrique Sergio Coelho, Markus Cornberg, Matthew Cramp, Gregory J. Dore, Wahid Doss, Ann‐Sofi Duberg, Manal H. El‐Sayed, Gül Ergör, Gamal Esmat, Chris Estes, Karolin Falconer, J Félix, Maria Lúcia Gomes Ferraz, Paulo Roberto Abrão Ferreira, Soňa Fraňková, Javier García‐Samaniego, Jan Gerstoft, José Gíria, Fernando Lopes Gonçales, E. Gower, Michael Gschwantler, Mário Guimarães Pessôa, Christophe Hézode, Heribert Hofer, Petr Husa, Ramazan Idılman, Martin Kåberg, K. Kaita, Achim Kautz, Sabahattin Kaymakoğlu, Mel Krajden, Henrik Krarup, Wim Laleman, Daniel Lavanchy, Pablo Lázaro, Paul Marotta, Stefan Mauss, Maria Cássia Mendes Corrêa, Beat Müllhaupt, Robert P. Myers, Francesco Negro, Vratislav Němeček, Necati Örmecı, Julie Parkes, Kevork Peltekian, Alnoor Ramji, Homie Razavi, Nathalia Rodrigues dos Reis, Stuart K. Roberts, William Rosenberg, Rui Sarmento‐Castro, C. Sarrazin, David Semela, Gamal Shiha, William Sievert, Peter Stärkel, Rudolf Stauber, Alexander Thompson, Petr Urbánek, Ingo van Thiel, Hans Van Vlierberghe, Dominique Vandijck, W. Vogel, Imam Waked, Heiner Wedemeyer, Nina Weis, Johannes Wiegand, A. Yosry, Amany Zekry, Pierre Van Damme, Soo Aleman, S. J. Hindman

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Viral Hepatitis · 2014
Typereview
Languageen
FieldMedicine
TopicHepatitis C virus research
Canadian institutionsQueen Elizabeth II Health Sciences CentreUniversity of CalgaryUniversity of TorontoWestern UniversityBC Centre for Disease ControlUniversity of British ColumbiaUniversity of ManitobaUniversité de MontréalDalhousie UniversityCapital District Health AuthorityHealth Sciences CentreUniversity Health NetworkToronto General Hospital
FundersPublic Health EnglandNational Institute for Health and Care ResearchGilead Sciences
KeywordsVirologyEpidemiologyHepatitis C virusHepatitis virusVirusHepatitis a virusEnvironmental healthMedicineInternal medicine

Abstract

fetched live from OpenAlex

Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3% in Austria, England and Germany to 8.5% in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.019
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.922
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.019
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0100.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.068
GPT teacher head0.389
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it