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Record W2055080580 · doi:10.1109/isie.2006.295999

A Dynamic Model and Analysis of a Single Biological Cell

2006· article· en· W2055080580 on OpenAlexaff
Marjan Molavi, Ion Stiharu

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCellular Mechanics and Interactions
Canadian institutionsConcordia University
Fundersnot available
KeywordsFinite element methodModulusElasticity (physics)RADIUSYoung's modulusMaterials scienceBulk modulusElastic modulusWork (physics)Dynamic modulusMechanicsStructural engineeringDynamic mechanical analysisComposite materialPhysicsComputer scienceThermodynamicsEngineering

Abstract

fetched live from OpenAlex

The relationship between composition and structure of primary cell walls, and cell mechanical properties is not fully understood because intrinsic properties of walls such as Young's modulus cannot be readily obtained. The aim of this work is to show that Young's modulus of walls of single yeast cell can be determined by dynamic modeling and analyzing the cell by finite element methods. In this investigation a spherical membrane was defined to benchmark an idealized shape model for yeast cell. Based on the open literature a resonant frequency in the range of 0.8 to 1.6 kHz was assumed for this benchmark cell. Mechanical properties of the cell have been investigated by substituting different modulus of elasticity, radius, density and thickness to fine-tune the results within the range of assumed periodic motions. The effect of different parameters such as, radius, density, thickness and modulus of elasticity on frequency was further investigated through dynamic performance analysis using FEA, in this case ANSYS. The results show that the experimental and the FEM approach agree with each other in some parameters within a reasonable band

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.004
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.225
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2006
Admission routes1
Has abstractyes

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