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Record W2055523973 · doi:10.1103/physreve.65.051901

Impact of regulatory proteins on the nonlinear dynamics of DNA

2002· article· en· W2055523973 on OpenAlexafffund
M. V. Satarić, Jack A. Tuszyński

Bibliographic record

VenuePhysical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics · 2002
Typearticle
Languageen
FieldPhysics and Astronomy
TopicSpectroscopy and Quantum Chemical Studies
Canadian institutionsUniversity of Alberta
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsBreatherChain (unit)Nonlinear systemDNABase pairDynamics (music)PhysicsStatistical physicsMolecular dynamicsChemical physicsQuantum mechanicsBiologyGenetics

Abstract

fetched live from OpenAlex

In this paper we examine the nonlinear dynamics of a DNA chain whose exciton modes are affected by regulatory proteins that may become bound to the DNA chain by hydrogen bonds. The dynamics of the DNA chain is described by the Peyrard-Bishop model. Since this model gives rise to large-amplitude broad oscillations of base pairs, we consider the impact of attached regulatory proteins on the so-called breathers or bubbles. Assuming that an ideal gas of bubbles may exist in the DNA chain at physiological temperatures we adopt a statistical approach to calculate the average size of base-pair stretching under the prevailing conditions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.138
Threshold uncertainty score0.927

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.310
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations16
Published2002
Admission routes2
Has abstractyes

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