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MEDICAL AND NEURO-ONCOLOGY
Gopi Kesaria Prithviraj, S. R. Sommers, Robin Jump, Balázs Halmos, Lola B. Chambless, Stacey L. Parker, Laila Hassam-Malani, Matthew J. McGirt, R. C. Thompson, K. Hunter, Evans Le, Eun-Yeup Lee, Z. S. Sadighi, Michael Pearlman, John M. Slopis, Tribhawan S. Vats, S. Khatua, Nicholas C. DeVito, Mingwei Yu, R. Chen, Eddie Pan, Timothy F. Cloughesy, J. Drappatz, Margie Gerena-Lewis, Jaqueline Willemann Rogerio, S. Yacoub, Amaury Desjardin, Morris D. Groves, John DeGroot, Monica Loghin, Claudius Conrad, K. R. Hess, Jianjiao Ni, Sandra Ictech, W. A. Yung, A. B. Porter, A. C. Dueck, N. J. Karlin, Jonathan R. Olson, J. R. Silber, Anne S. Reiner, K. Panageas, F. M. Iwamoto, Kenneth Aldape, A. L. Rivera, April F. Eichler, David N. Louis, Nina A. Paleologos, B. J. Fisher, Landon Ashby, J. Gregory Cairncross, Glòria Roldán, K. L. Ligon, D. Shiff, H. Ian Robins, Brandon G. Rocque, S. A. Weaver, F. G. Kamar, L. E. Abrey, Lisa M. DeAngelis, S.C. Jhanwar, David Cachia, Lloyd M. Alderson, R. L. Moser, Thomas G. Smith, Shakeeb Yunus, Kan Saito, Akitake Mukasa, Yukiya Narita, Yasue Tabei, Nobusada Shinoura, Soichiro Shibui, Naoya Saito, Birgit Flechl, Michael Ackerl, Cornelia Sax, Richard Crevenna, G. Widhalm, C. Marosi, Cihan Ay, Daniela Dunkler, Ingrid Pabinger, C. Zielinski, Meghan Belongia, Sachin Jogal, K.-H. Schlingensiepen, Ulrich Bogdahn, Günther Stockhammer, Anuspandana Mahapatra, N. K. Venkataramana, V. Oliushine, В. А. Парфенов, И. Е. Повереннова, Peter Hau, Piotr Jachimczak, H. Heinrichs, Aaron Mammoser, Nicole Shonka, John de Groot, Ichiyo Shibahara, Y. Sonoda, Tsutomu Kumabe, Ryuta Saito, Masayuki Kanamori, Yoshiaki Yamashita, Masato Watanabe, C. Ishioka, T. Tominaga, A. Silvani, Paola Gaviani, E. Lamperti, A. Botturi, Francesco DiMeco, Giuseppe Broggi, Laura Fariselli, C. L. Solero, A. Salmaggi, E. A. Woyshner, Fangpeng Shu, Young S. Oh, S. Iganej, Gaurav Singh, Suresh Vemuri, Brett Theeler, Benjamin Ellezam, M. R. Gilbert, Tomokazu Aoki, H. Kobayashi, Shingo Takano, Ryo Nishikawa, Motoo Nagane, Y. Muragaki, K. Sugiyama, J. Kuratsu, M Matsutani, Lauren A. Langford, Vinay K. Puduvalli, Zhi‐Gang She, Z.-p. Chen, J.-p. Zhang, D. Bedekar, Scott D. Rand, James A. Connelly, Mark G. Malkin, E K Paulson, Wade M. Mueller, K. Schmainda, O. Gallego, M. Benavides, P. P. Segura, C. Balana, M. Gil, A. Berrocal, Gaspar Reynés, Jorge Luis García-Alcaráz, Paola Murata, S. Bague, M. J. Quintana, V. G. Vasishta, K. Kobayashi, M. Tanaka, Kazuo Tsuchiya, Y Shiokawa, Abhi Bavle, K. Ayyanar, Marta Penas Prado, Kenneth R. Hess, V. Liu, J. de Groot, M. E. Loghin, V. A. Levin, J. R. Hackney, Cheryl A. Palmer, James M. Markert, J K Curé, Kathy Riley, Hassan M. Fathallah‐Shaykh, L. B. Nabors, Marlon Garzo Saria, Courtney Corle, Jim C. Hu, Jeremy Rudnick, Surasak Phuphanich, Maciej M. Mrugała, L. K. Lee, R. Y. Kim, Taylor Brown, Homira Feely, Aiguo Patrick Hu, Jae Wook Lee, B. Carter, Xiao–Tang Kong, Steven Sparagana, Е. В. Белоусова, S. Jozwiak, Bruce R. Korf, Markus Winther Frost, Rachel Kuperman, Michael Kohrman, Olaf Witt, Jie Wu, R. Flamini, A. Jansen, P. Curtalolo, Elizabeth A. Thiele, Vicky Whittemore, Petrus de Vries, J. Ford, Gaurav Shah, Helene Cauwel, Pascal Edrich, Tarek Sahmoud, David R. Franz, M. Khasraw, Chris Brown, David M. Ashley, Mark Rosenthal, Xiaodong Jiang, Yong Mou, Zesheng Chen, M. Oh, E. kim, Joe H. Chang, T. A. Juratli, Matthias Kirsch, Gabriele Schackert, Dietmar Krex, R. Stupp, Monika E. Hegi, Kurt A. Jaeckle, T. Armstrong, J. S. Wefel, Minhee Won, Deborah T. Blumenthal, Anita Mahajan, C.J. Schultz, S. C. Erridge, Paul D. Brown, A. Chakravarti, William J. Curran, Minesh P. Mehta, Kenneth Francis Hofland, Søren B. Hansen, Heather Yarnall Schultz, Aida Muhic, S. Engelholm, Anna Ask, Charlotte Kristiansen, Caroline Brenner Thomsen, Hans Skovgaard Poulsen, Ulrik Lassen, C. Weston, Syed Rahmanuddin, Mark S. Shiroishi, Steven Cen, Jessica Treviño Jones, T. Chen, P Pagnini, Jorge Go, A. Lerner, Jorge Gómez, Z. Ram, Eric T. Wong, P. H. Gutin, M. S. Bobola, Mohammed Alnoor, Daniel L. Silbergeld, Robert Rostomily, Nakaye Martha, Saulam Jacqueline, G. Thaddaus, P. Daniel, Michael Hans, M. Armin, Sven Günther, Markus Hutterer, Hsiao‐Jung Tseng, C. M. Zoccoli, Omar Zalatimo, Ashit Patel, Kathryn Rizzo, J. Sheehan, Ashley Sumrall, James J. Vredenburgh, Annick Desjardins, D. A. Reardon, H. S. Friiedman, Klaus Peters, L. P. Taylor, Mackenzie Stewart, N. A. Blondin, Joachim M. Baehring, Trevor Foote, Nadia N. Laack, Jason A. Call, M. G. Hamilton, S. Walling, Misha Eliasziw, Jacob C. Easaw, Neelam Shirsat, R. Kundar, Abhay S. Gokhale, A. Goel, A. A. Moiyadi, Jian Wang, Emel Mutlu, Anne M. Øyan, Tao Yan, Oleg Tsinkalovsky, Hege Karine Jacobsen, K. M. Talasila, Linda Sleire, Kristin Pettersen, H. Miletic, S. Andersen, S. Mitra, I. L. Weissman, X. Li, Karl H. Kalland, P. O. Enger, Juan Manuel Sepúlveda-Sánchez, Cristóbal Belda-Iniesta, Pedro Pérez Segura, R. Sitt, L. Phishniak, F. Bokstein, C. Carole, Marc André, B. Marylin, C. Olivier, O. L'Houcine, N.-M. Isabelle, Florence Frédéric, Fromentin Stéphane, Dave Henry, Michela Errico, Lara J. Kunschner, Riccardo Soffietti, Elisa Trevisan, Roberta Rudà, Luca Bertero, Chiara Bosa, Mariagrazia Fabrini, Ivan Lolli, R. Jalali, P. K. Julka, Ajeya Anand, D. Bhavsar, Niti Singhal, Raj Naik, Shaughnessy John, Beela Sarah Mathew, Iyavut Thaipisuttikul, J. Graber, Mihran Shirinian, Adam M. Fontebasso, Koshy Jacob, Nashaat Z. Gerges, Alexander Montpetit, A. Nantel, Sybille Albrecht, N. Jabado, Kaustav P. Shah, Korotkov Di, M. Linskey, Niklas Thon, Sabina Eigenbrod, Simone Kreth, J. Lutz, J.-C. Tonn, Hans Kretzschmar, Aurelia Peraud, Friedrich-Wilhelm Kreth, A. D. Muggeri, Juan Pablo Alderuccio, Blanca Diez, P. Jiang, Yaqing Chao, M. Gallagher, R. Kim, Sara Pastorino, Valentina Fogal, Catherine Bresee, André Rogatko, S. Sakowsky, Mayra Alvarez Franco, Sung-Jig Lim, A. Lopez, Li Yu, K. Ryback, Vivian Tsang, Michael Lill, A D Steinberg, Rahul Sheth, Irene Helenowski, J. Raizer, Fabio P. Nunes, Vanessa L. Merker, Danna Jennings, Paul A. Caruso, Alona Muzikansky, Anat Stemmer‐Rachamimov, Scott R. Plotkin, A. Spalding, T. W. Vitaz, Deyu Sun, SK Parsons, Mary Welch, A. Omuro, K. Beal, D. Correa, Timothy A. Chan, Igor T. Gavrilovic, C. Nolan, A. Hormigo, Thomas Kaley, I. Mellinghoff, Katherine S. Panageas, A. Reiner, R. Barradas, Lauren E. Abrey, Philip H. Gutin, S. Y. Lee, Becky Slagle‐Webb, M. J. Glantz, J. R. Connor, Claudia Schlimper, H. Schlag, G. Stoffels, F Weber, D. A. Krueger, Marguerite M. Caré, Kent Holland, Karen Agricola, Cynthia Tudor, Anna W. Byars, D. N. Franz, L. Rice, Alfred Rademaker, J. Chandler, K. Muro, Lakshmi Nayak, A. D. Norden, Alissa A. Thomas, C. E. Fadul, Leonard Meyer, E. C. Lallana, M. Gilbert, K. Aldape, Joris R. de Groot, S. Nagpal, Abdullah Feroze, L. Recht, Hemalatha G. Rangarajan, Mark W. Kieran, Robert McN. Scott, Si Min Lew, Semra Fırat, Analía Segura, Priya Kumthekar, Sean Grimm, Michael J. Avram, J. Patel, V. Kaklamani, K. McCarthy, M. Cianfrocca, W. Gradishar, M. Mulcahy, Jamie Von Roenn, Evanthia Galanis, S. K. Anderson, Jackie M. Lafky, Timothy J. Kaufmann, Joon H. Uhm, C. Giannini, Seema Kumar, Donald W. Northfelt, Patrick J. Flynn, J. C. Buckner, A. I. Omar, P. Y. Wen, D. Schiff, R. M. Green, A. B. Lassman, Andrew Delios, A. Jakubowski, Isaac Melguizo‐Gavilanes, X. Wang, Neda Hashemi‐Sadraei, Harpreet S. Bawa, Gazanfar Rahmathulla, Paul Elson, G. Stevens, D. Peereboom, Michael Vogelbaum, Ruben Weil, Gene H. Barnett, Manmeet S. Ahluwalia, Ellsworth C. Alvord, Russell C. Rockne, Jason K. Rockhill, Maciej Mrugala, Albert Lai, Joanna M. Wardlaw, A. M. Spence, Gelareh Zadeh, Hussein Alahmadi, Joanne A. P. Wilson, F. Gentili, J. J. Beumer, James R. Wright, Noriko Takebe, R. Gaur, Maria Werner‐Wasik, A. J. Gupta, Angel F Campos-Gines, Komarova Le, Celso Arango, Michael Richards, Mark M Landeros, Hsueh‐Fen Juan, J. S. Kim, J. H. Cho, Anne Baldock, Peter Canoll, Donald E. Born, Kevin Yagle, D. Alexandru, Daniela A. Bota, M. E. Linskey, Shaha Nabeel, Sumul Raval, Louise Rice, Joshua M. Rosenow, Markus Bredel, Pamela New, Jeffrey G. Supko, William T. Curry, Adewole A.S, E. R. Gerstner, T. T. Batchelor, Neda Hashemi, S.T. Chao, Jung H. Suh, Michael A. Vogelbaum, Glen Stevens, D. Corwin, C D Holdsworth, R.D. Stewart, Kristin R. Swanson, J. J. Graber, A. R. Anderson, S. Jeyapalan, Max L. Goldman, Jerrold L. Boxerman, John K. Donahue, Heinrich Elinzano, Dean B. Evans, B.M. O’Connor, Mohamed Y Puthawala, Adetokunbo A. Oyelese, Deus Cielo, M. Blitstein, M. Dargush, A. Santaniello, Maria Constantinou, T.A. DiPetrillo, H. Safran, Christopher F. Halpin, F. G. Barker, E. A. Maher, Sandeep Ganji, R. DeBerardinis, Kimmo J. Hatanpaa, D. Rakheja, Xinshun Yang, Tooru Mashimo, J. Raisanen, Ciara Madden, Bruce Mickey, Craig R. Malloy, Robert Bachoo, CH Choi, Tushar Ranjan, Novi Heri Yono, S. J. Han, Mingyao Sun, M. S. Berger, Manish K. Aghi, Neeti Gupta, A. T. Parsa
Bibliographic record
VenueNeuro-Oncology · 2011
Typearticle
Languageen
FieldMedicine
TopicMedical and Biological Sciences
Canadian institutionsMcGill UniversityDalhousie UniversityUniversity of Calgary
Fundersnot available
KeywordsMedicineInternal medicineOncology
Abstract
Leptomeningeal carcinomatosis is a devastating complication of malignancy and is rarely seen in esophageal carcinoma. Herein we describe a patient who was found to have not only leptomeningeal carcinomatosis from esophageal adenocarcinoma but also concurrent Pediococcus bacterial meningitis. A sixty-six year old man with known esophageal adenocarcinoma, which was previously treated with 5-fluorouracil and cisplatin with concurrent radiation therapy followed by transhiatal esophagectomy, presented sixteen months after initial treatment with failure to thrive and headache for one month. Diagnostic testing of cerebrospinal fluid revealed adenocarcinoma by cytology and Pediococcus species by culture. Pediococcus causing meningitis is uncommon, previously having been described in only one case report in the English literature. The concurrent finding of both of these conditions in our patient is extremely unusual. It is unknown if the concurrent conditions of leptomeningeal carcinomatosis and Pediococcus meningitis are related or independent conditions. We postulate several possible mechanisms for the causation of this unusual presentation and review recent literature regarding the treatment of these conditions.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.913
Threshold uncertainty score0.995
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.006 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
Opus teacher head0.065
GPT teacher head0.326
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
Study designNot applicable
Domainnot available
GenreEmpirical
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".
Quick stats
Citations2
Published2011
Admission routes1
Has abstractyes