Delayed Weaning and Denial of Solid Food Nibbling upon Pancreatic Acinar Cell Responsiveness to Urecholine in Neonatal Rats
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Pancreatic response to urecholine was studied in rats which were fed maternal milk only until they reached 27 days of age. A group of pups which remained all the time with their mother were weaned at 21 days; over that nursing period, their pancreatic amylase concentration increased gradually, lipase started to decrease from day 23 while chymotrypsin remained constant. In those who were denied solid food from day 12, the amylase concentration fell significantly from day 23 to 27 while lipase and chymotrypsin rose rapidly. Delayed weaning was associated with significant decreases in basal and urecholine-stimulated amylase secretion from day 23, whereas lipase and chymotrypsin releases were increased. If, however, secretion is expressed in percentages of the amount of enzyme released over the total tissue content, the output of the three enzymes in response to urecholine is significantly reduced from day 25 in pups kept on maternal milk only. These results suggest that dietary fat and carbohydrate modulate the enzyme content of the pancreas and that milk as the only source of energy and protein reduces the pancreatic acinar cell responsiveness to urecholine.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it