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The history and future of targeting cyclin-dependent kinases in cancer therapy

2015· review· en· 1,762 citations· W2057272791 on OpenAlex· 10.1038/nrd4504

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Reviews Drug Discovery
Topic
Advanced Breast Cancer Therapies
Field
Medicine
Canadian institutions
Funders
National Cancer InstituteConsortium canadien en neurodégénérescence associée au vieillissementCancer Research UKF. Hoffmann-La RocheBristol-Myers Squibb
Keywords
KinaseCyclinCancer researchTargeted therapyCancerCyclin-dependent kinaseCancer therapyMedicineOncologyBiologyInternal medicineCell biologyCell cycle
Has abstract in OpenAlex
no