Current status of potential organ donation in cases of lethal fetal anomaly
Bibliographic record
Abstract
Key content Anencephaly is the most severe form of neural tube defect with most pregnancies terminated following antenatal diagnosis and those carrying to term often stillborn. Organ donation following anencephalic live birth has been undertaken worldwide, especially in the early years of infant transplantation. In theUSAand Canada this ceased towards the end of the last century. Although fewUKtransplants occurred, and the practice has ceased, national guidelines still support organ retrieval from anencephalic babies once certified dead. With the current organ donation task‐force linked drive, obstetricians are increasingly confronted with women carrying anencephalic fetuses who decline termination, perhaps for religious reasons, who would like to consider donation. Anencephalic donation does not occur in theUK, or indeed worldwide at present. Learning objectives This paper seeks to review the currentUKposition and possible developments, and to provide guidance for obstetricians to reply to such requests. Ethical issues Can a pregnant women elect for her anencephalic infant to be managed in such a manner – with organ support at delivery – that eventual donation after circulatory death can provide organs for others on the subsequent death of the baby?
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.004 | 0.021 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.002 | 0.003 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.007 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".