<title>FDTD modelling of the cell membrane and gold nanoparticles effects on optical immersion experiments</title>
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
The FDTD modeling technique is applied to provide additional insight on the effect of the cell membrane thickness in optical immersion enhanced phase contrast microscope imaging. Pilot results on the application of the FDTD approach for studying the implementation of the optical immersion technique for the visualization of single and multiple gold nanoparticles in biological cells are also presented. The paper focuses on three different scenarios considering single biological cells containing i) cytoplasm and membrane, ii) cytoplasm, nucleus and membrane, and iii) cytoplasm, nucleus, gold nanoparticle(s) and membrane. To the best knowledge of authors, this is the first research study discussing the cell membrane thickness and single gold nanoparticle effects on the forward scattered light from biological cells. The potential of the FDTD approach and its applicability to new and promising biomedical optics research areas such as the study of optical immersion technique enhanced bio-imaging is demonstrated.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it