MétaCan
Menu
Back to cohort
Record W2059614606 · doi:10.1002/3527603948.ch15

Combinatorial Chemistry in the Age of Chemical Genomics

2004· other· en· W2059614606 on OpenAlexaff
Reni Joseph, Prabhat Arya

Bibliographic record

VenueMethods and principles in medicinal chemistry · 2004
Typeother
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicChemical Synthesis and Analysis
Canadian institutionsSteacie Institute for Molecular Sciences
FundersNational Cancer Institute
KeywordsNatural productProduct (mathematics)Diversity (politics)Natural (archaeology)Computational biologyGenomicsChemistryComputer scienceCombinatorial chemistryBiologyStereochemistryMathematicsBiochemistrySociologyGenomeGeneAnthropologyPaleontology

Abstract

fetched live from OpenAlex

This chapter contains sections titled: Introduction Combinatorial Approaches to Natural Product Analogs Diversity-oriented Synthesis of Natural-product-like Libraries Conclusions

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.436
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.321
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2004
Admission routes1
Has abstractyes

Explore more

Same venueMethods and principles in medicinal chemistrySame topicChemical Synthesis and AnalysisFrench-language works237,207