Cronkhite-Canada-Syndrom: Eine seltene Ursache chronischer Diarrhoe mit enteralem Eiweissverlust
Bibliographic record
Abstract
Das Cronkhite-Canada-Syndrom ist eine seltene nichtneoplastische Polypose-Erkrankung des gesamten Darmrohrs, kompliziert durch lebensbedrohlichen Eiweissverlust. Insgesamt wurden seit der Erstbeschreibung 1955 weltweit mehr als 400 Fälle berichtet. Die Ursache und Pathogenese liegen im Unklaren. Ein 71jähriger Patient präsentierte sich nach mehrwöchiger Diarrhoe mit einem Serumalbumin von 1,9g/dl und einem Serumgesamteiweiss von 3,8g/dl. Die klinische Untersuchung zeigte deutliche Unterschenkelödeme. Weiters konnten auch die für Cronkhite-Canada-Syndrom typischen Hautveränderungen (periaurikuläre Alopezie, Finger- und Zehennagelveränderungen, Hyperpigmentierung) gefunden werden.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.002 | 0.002 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.001 | 0.003 |
| Insufficient payload (model declined to judge) | 0.006 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".