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Moving to tolerance: Clinical application of T regulatory cells

2011· review· en· 100 citations· W2061692532 on OpenAlex· 10.1016/j.smim.2011.04.001

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

The three-model screen

all 1,000 screened works →

All three models called this out of scope.

stratum: aff_core · design weight: 5595.24 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high

Immunology review of clinical application of regulatory T cells; domain science.

GPT-5.6 (high)OUT
genre: conceptual
about Canada: no
confidence: low

The abstract is missing and the title indicates a clinical immunology review, not an unambiguous study of research.

Grok 4.5OUT
genre: empirical
about Canada: no
confidence: high

Clinical immunology review of T regulatory cell therapy; title alone places it outside metaresearch.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Seminars in Immunology
Topic
T-cell and B-cell Immunology
Field
Immunology and Microbiology
Canadian institutions
Child and Family Research InstituteUniversity of British Columbia
Funders
Canadian Institutes of Health ResearchRoche Organ Transplant Research FoundationBritish Heart FoundationWellcome Trust
Keywords
ImmunosuppressionMedicineImmunologyTransplantationRegulatory T cellCell therapyIntensive care medicineT cellImmune systemBiologyStem cellIL-2 receptorInternal medicineCell biology
Has abstract in OpenAlex
no