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Principal Component Analysis for Protein Folding Dynamics

2008· article· en· 489 citations· W2062105576 on OpenAlex· 10.1016/j.jmb.2008.10.018

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.010
GPT teacher head0.266
Teacher spread
0.256 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Journal of Molecular Biology
Topic
Protein Structure and Dynamics
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Funders
Fogarty International CenterNational Institute of General Medical SciencesInstitut de Cardiologie de MontréalCornell UniversityNational Institutes of HealthNational Science Foundation
Keywords
Protein foldingFolding (DSP implementation)Principal component analysisStatistical physicsContact orderNative stateProtein dynamicsPhysicsDownhill foldingBrownian dynamicsDynamics (music)Energy landscapeMolecular dynamicsChemistryCrystallographyBiological systemBrownian motionMathematicsPhi value analysisComputational chemistryThermodynamicsBiologyStatisticsBiochemistryEngineering
Has abstract in OpenAlex
no