Takotsubo Cardiomyopathy and Acute Ischemic Stroke
Bibliographic record
Abstract
Takotsubo cardiomyopathy and acute ischemic stroke. The Takotsubo cardiomyopathy is characterized by transient left ventricle dysfunction, with apical ballooning in the absence of significant coronary stenosis, and may clinically mimic an acute myocardial infarction. The association between Takotsubo cardiomyopathy and several acute neurological conditions has been increasingly described. The authors present the case report of an acute stroke patient submitted to intravenous thrombolysis, whose EKG on admittance showed supra-ST deviation in DI, AVL and V2-V6 leads, with concomitant elevation of myocardial necrosis biomarkers. After intravenous thrombolysis, a cardiac catheterism was performed that showed apical ballooning and acinesia of the left ventricle with decreased ventricular function, with no significant coronaropathy. The cerebral MRI performed on the seventh day showed multiple acute infarctions in different vascular territories of the anterior and posterior circulations bilaterally. Transthoracic echocardiogram performed on the same day revealed normal ventricular function and myocardial kinetics supporting the diagnosis of Takotsubo cardiomyopathy. The patient was discharged on day 10, on hypocoagulation therapy. Takotsubo cardiomyopathy is a spontaneously reversible condition, mostly requiring supportive therapeutic measures. The acute left ventricle dysfunction characteristic of this syndrome is a potential mechanism for cardiac embolism. Acute ischemic stroke is a relatively rare but severe complication. According to this, hypocoagulant therapy must be considered especially until the ventricular function is fully recovered. doi: http://dx.doi.org/10.4021/jmc776w
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".