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Record W2062597765 · doi:10.1159/000231274

In vitro Cellular Immunity and in vivo Delayed Hypersensitivity in Uremic Patients Maintained on Hemodialysis

2009· article· en· W2062597765 on OpenAlexaff
D.P.S. Sengar, Abdur Rashid, Jules E. Harris

Bibliographic record

VenueInternational Archives of Allergy and Applied Immunology · 2009
Typearticle
Languageen
FieldMedicine
TopicFood Allergy and Anaphylaxis Research
Canadian institutionsOttawa HospitalUniversity of Ottawa
Fundersnot available
KeywordsMedicineIn vivoStreptokinaseIn vitroDelayed hypersensitivityHemodialysisImmunologyLymphocyteAntigenInternal medicinePharmacologyChemistryBiology

Abstract

fetched live from OpenAlex

Uremic patients on hemodialysis for periods in excess of 1 year have a significantly better survival rate for their renal allografts than do similar patients hemodialyzed for less than 1 year. Lymphocytes from the patients of both groups show no difference in response in the mixed leukocyte culture reaction and to nonspecific mitogens such as PHA and PWM. A significant difference between the two groups of patients was observed with regard to their cutaneous delayed hypersensitivity reactions and in their in vitro lymphocyte responses to streptokinase-streptodornase. Patients hemodialyzed over 1 year were anergic to skin test antigens and had a significantly diminished in vitro response to streptokinase-streptodornase. Monitoring of patients for delayed cutaneous hypersensitivity reactions and for in vitro lymphocyte responses to streptokinase-streptodornase may be of some practical value in selecting recipients for renal transplantation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.748
Threshold uncertainty score0.502

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.232
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations37
Published2009
Admission routes1
Has abstractyes

Explore more

Same venueInternational Archives of Allergy and Applied ImmunologySame topicFood Allergy and Anaphylaxis ResearchFrench-language works237,207