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Record W2062670617 · doi:10.4088/jcp.9089tx1cc

Long-Term Treatment of Bipolar Disorder in Adults

2011· article· en· W2062670617 on OpenAlexaff
Roger S. McIntyre

Bibliographic record

VenueThe Journal of Clinical Psychiatry · 2011
Typearticle
Languageen
FieldMedicine
TopicBipolar Disorder and Treatment
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsBipolar disorderPsychiatryPharmacotherapyMedicineQuality of life (healthcare)ComorbidityMajor depressive disorderPsychologyLithium (medication)PsychotherapistMood

Abstract

fetched live from OpenAlex

Bipolar disorder is a common, chronic, multidimensional syndrome that appears to be a progressive illness, in that each episode substantially increases the risk that another episode will occur and will be less responsive to treatment than previous episodes. The biphasic and episodic nature of bipolar disorder substantially contributes to its negative impact on patients' quality of life as well as their physical, social, and occupational functioning. Patients with bipolar disorder often have co-occurring conditions, particularly medical comorbidities, and, unfortunately, several psychotropic medications prescribed to treat bipolar disorder may increase the risk of developing certain medical illnesses. Although the recommendation in psychiatric care is to regularly assess patients' physical health, many clinicians are not yet implementing this strategy in their clinical practice. When making evidence-based medication choices, clinicians can select from several FDA-approved agents for the treatment of acute manic and depressive episodes as well as for maintenance therapy. Additionally, psychotherapies are effective when used in combination with pharmacotherapy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.058
GPT teacher head0.376
Teacher spread0.317 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2011
Admission routes1
Has abstractyes

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