Bibliographic record
Abstract
Abstract We have previously observed in vivo that chronic AlCl3 exposure in young adult New Zealand white rabbits induces a reversible motor neuron degeneration. In addition to the development of neurofilamentous aggregates within degenerating neurons, we have also observed a reduction of microglial number and activation. To determine if aluminum could directly effect microglial function in vivo, we used an immortalized murine microglial cell line (BV‐2) to study the effect of organic (aluminum lactate) and inorganic (AlCl3) compounds on microglial function. We have observed a dose‐dependent inhibition of phagocytosis, proliferation, migration, and release of TNF‐α and nitric oxide in the absence of inducing microglial death. Both organic and inorganic aluminum decreased the extent of LPS‐activated microglia‐mediated death of a motor neuron hybridoma cell line (NSC 34). These findings demonstrate that aluminum compounds can directly affect microglial in vitro. J. Trace Elem. Exp. Med. 15:141–152, 2002. © 2002 Wiley‐Liss, Inc.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".