Auxin signal transduction in Arabidopsis vein formation
Bibliographic record
Abstract
The plant signaling molecule auxin has been implicated in the control of a confounding multitude of diverse processes in plants, including leaf vascular patterning. In Arabidopsis leaves, expression of the HD-ZIP III gene ATHB8 is initiated in files of isodiametric subepidermal cells that will elongate into vein-forming procambium. We have recently shown that ATHB8 is transiently required for preprocambial development and procambium differentiation, and that permanence of the effects of loss of ATHB8 function on vein formation depends on the activity of the auxin response factor MONOPTEROS (MP). Further, we have shown that the onset of ATHB8 expression is directly and positively regulated by MP through an auxin-response element in the ATHB8 promoter, suggesting a molecular path by which auxin signals are translated into vein patterning inputs. Within broad fields of MP expression, however, only a subset of cells initiates expression of ATHB8. Here we discuss putative mechanisms by which wide domains of MP expression could activate ATHB8 transcription in single cell files.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.003 | 0.002 |
| Insufficient payload (model declined to judge) | 0.003 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".