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Record W2064065946 · doi:10.1159/000178664

Changes in Gonadotropin Secretion following Complete or Hemicastration in the Adult Rat

2008· article· en· W2064065946 on OpenAlex
B. E. Howland, Kate Skinner

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueHormone Research · 2008
Typearticle
Languageen
FieldMedicine
TopicSperm and Testicular Function
Canadian institutionsUniversity of Manitoba
Fundersnot available
KeywordsCastrationInternal medicineEndocrinologyTestosterone (patch)Compensatory hypertrophyAdult maleMuscle hypertrophyGonadotropinSecretionMedicineBiologyHormone

Abstract

fetched live from OpenAlex

The effect of sham castration, hemicastration or complete castration on gonadotropin and testosterone secretion was studied in adult male rats. Untreated control rats were autopsied 1, 10, 20, 30 and 40 days following assignment to treatment groups. Sham-castrated controls were autopsied 1, 2 and 3 days after surgery. Complete and hemicastrates were autopsied 1, 2, 3, 10, 20, 30 and 40 days after surgery. Serum levels of both FSH and LH were elevated by 24 h postcastration and the levels of both gonadotropins continued to rise throughout the course of the experiment. Serum levels of LH rose following hemicastration and remained above control values through day 30. Serum FSH levels were not significantly affected by hemicastration. Compensatory testicular hypertrophy was not observed in hemicastrated rats.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.844
Threshold uncertainty score0.196

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.150
GPT teacher head0.370
Teacher spread0.219 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it