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Record W2065274254 · doi:10.1136/bmj.327.7426.1237

What do we gain from the sixth coronary heart disease drug?

2003· letter· en· W2065274254 on OpenAlexaff
Rebecca Warburton

Bibliographic record

VenueBMJ · 2003
Typeletter
Languageen
FieldEconomics, Econometrics and Finance
TopicHealth Systems, Economic Evaluations, Quality of Life
Canadian institutionsUniversity of Victoria
Fundersnot available
KeywordsPerfectionSAFERHarmHealth careIdeal (ethics)BusinessRisk analysis (engineering)MedicineComputer securityComputer scienceEconomicsLawPolitical scienceEconomic growth

Abstract

fetched live from OpenAlex

Not much: guidelines must consider cost effectiveness From air travel to patient safety to coronary heart disease prevention, people strive to reduce risk to zero. We know that zero risk is unattainable, yet we pursue perfection. It may be useful to hold perfection as an ideal,1 but there can be great harm in trying to achieve it because near perfection often imposes near infinite costs. The closer we get to perfect risk reduction, the more likely it becomes that we could have got a better bang for our preventive buck somewhere else. This applies across all activities–and needs to be heeded in health care as anywhere else. For example, air travel is already much safer than most other forms of travel, so £10m ($17m; €14m) spent on road safety would save far more life years than £10m put into tightening airport security. Yet since September 11 much new spending has gone into airport security. In health too we often see a rush to perfection without regard for costs. Here are three examples. Firstly, universal precautions to prevent worksite transmission of HIV to healthcare workers have been widely implemented, yet cost …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.047
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.037
Threshold uncertainty score0.052

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.047
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0020.003
Scholarly communication0.0030.006
Open science0.0010.001
Research integrity0.0370.026
Insufficient payload (model declined to judge)0.0160.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.263
GPT teacher head0.406
Teacher spread0.143 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2003
Admission routes1
Has abstractyes

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