Estimation of pulse transit time using two diametric blood pressure waveform measurements
Why this work is in the frame
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Bibliographic record
Abstract
This paper presents a novel method to estimate the aortic-to-peripheral pulse transit time (PTT) using the blood pressure waveforms measured at two diametric peripheral locations, for instance, one on an upper extremity and the other on a lower extremity. The method is based on a computational relationship between the two peripheral blood pressures, which is derived by first relating each peripheral blood pressure to a common central aortic blood pressure. The parameters of the computational relationship for an individual subject can be identified by fitting them to two peripheral blood pressure waveform measurements, thereby characterizing the cardiovascular dynamics, from which absolute changes in the PTT between the central aorta and each peripheral measurement site can be determined. The strength of the method is that it does not require any a priori knowledge of the peripheral measurement locations nor of the physiologic condition of the cardiovascular system. Experimental results are provided from five healthy swine subjects whose actual PTT experimentally varied from 44.9 ms to 163.0 ms (76.7 ms mean+/-26.4 ms SD). Compared to the reference PTT measurement, the novel method proposed in this paper estimated PTT within 3.7 ms mean+/-4.2 ms SD after initial calibration.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it