Sulfanilamide copper(II) chelates with 2-[(2-hydroxyphenyl-imino)methyl]phenolom and 1-[(2-hydroxyphenylimino)-methyl]naphthalen-2-ol
Bibliographic record
Abstract
2-[(2-Hydroxyphenylimino)methyl]phenol (H 2 L 1 ) and 1-[(2-hydroxyphenylimino)methyl]naphthalen-2-ol (H 2 L 2 ) reacted with copper(II) acetate hydrate and sulfanilamide (Sf 1 ), sulfathiazole (Sf 2 ), sulfaethidole (Sf 3 ), sulfadiazine (Sf 4 ), and sulfadimidine (Sf 5 ) in ethanol to give mixed-ligand copper chelates with the composition Cu(Sf 1–5 )(L 1–2 ) · n H 2 O ( n = 1, 2). All these complexes are monomeric. Salicylaldehyde imines (H 2 L 1 and H 2 L 2 ) behave as doubly deprotonated tridentate O,N,O ligands, whereas sulfanilamides (Sf 1–5 ) are unidentate ligands. Thermolysis of the synthesized complexes includes dehydration at 70–90°C, followed by complete thermal decomposition (290–380°C). The complexes [Cu(Sf 1 )(L 1 )] · 2H 2 O and [Cu(Sf 3 )(L 1 )] · H 2 O at a concentration of 10 −4 M inhibited growth and reproduction of 100% of human myeloid leukemia cells (HL-60). The inhibitory effect was 90 and 75%, respectively, at a concentration of 10 −5 M, whereas no antitumor activity was observed at a concentration of 10 −6 M.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".