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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

2012· review· en· 1,215 citations· W2065766094 on OpenAlex· 10.1038/ng.2249

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.056
GPT teacher head0.361
Teacher spread
0.305 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Genetics
Topic
Bone health and osteoporosis research
Field
Medicine
Canadian institutions
University of ManitobaHôpital Saint-François d'AssiseCentre hospitalier universitaire de QuébecUniversity of British ColumbiaMcGill University
Funders
National Center for Advancing Translational SciencesNational Institute of Arthritis and Musculoskeletal and Skin DiseasesNational Institute of Neurological Disorders and StrokeNational Cancer InstituteNational Human Genome Research InstituteNational Heart, Lung, and Blood InstituteInstituto de Salud Carlos IIIHealth Research Council of New ZealandCanadian Institutes of Health ResearchEli Lilly CanadaCollege of Pharmacy, University of MichiganNational Institutes of HealthHjartaverndKulturministerietNational Institute of Diabetes and Digestive and Kidney DiseasesTurun Yliopistollinen KeskussairaalaSyddansk UniversitetGöteborgs LäkaresällskapEmil Aaltosen SäätiöVetenskapsrådetPaavo Nurmen SäätiöAmgen CanadaCentre for Medical Systems BiologyNovo NordiskJuho Vainion SäätiöHealthwayKempe FoundationVersus ArthritisMinistry of Agriculture, Forestry and FisheriesNational Center for Research ResourcesNational and Kapodistrian University of AthensBundesministerium für Verkehr, Innovation und TechnologieNational Health and Medical Research CouncilJewish General HospitalSuomen KulttuurirahastoTampereen TuberkuloosisäätiöKelaMedical Research CouncilServierKing's College LondonAustralian Cancer Research FoundationGeelong Region Medical Research FoundationUniversity of MichiganFondation LeducqDairy Farmers of CanadaWorld Anti-Doping AgencySteirische WirtschaftsförderungsgesellschaftNational Institute for Health and Care ResearchCedars-Sinai Medical CenterAustrian Federal Ministry of Economy, Family and YouthNederlandse Organisatie voor Wetenschappelijk OnderzoekSvenska LäkaresällskapetArthritis SocietyStiftelsen för Strategisk ForskningNational Institute on AgingUniversity of Hong KongBritish Heart FoundationScottish GovernmentChronic Disease Research FoundationWellcome TrustProcter and GambleAmgenPfizerDonald W. Reynolds FoundationEli Lilly and CompanyErasmus Universitair Medisch Centrum RotterdamEuropean CommissionSanofi
Keywords
Genome-wide association studyBone mineralBiologyOsteoporosisBone densityGenetic associationGeneticsInternal medicineBioinformaticsSingle-nucleotide polymorphismEndocrinologyGeneMedicineGenotype
Has abstract in OpenAlex
no