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Cancer Metastasis and Cancer Stem Cells

2014· article· en· W2066194914 on OpenAlexvenueno aff
Huan Liu, Haijuan Wang, Haili Qian

Bibliographic record

VenueJournal of cancer research updates · 2014
Typearticle
Languageen
FieldMedicine
TopicCancer Cells and Metastasis
Canadian institutionsnot available
Fundersnot available
KeywordsMetastasisCancerCancer stem cellCancer metastasisCarcinogenesisCancer cellCancer researchStem cellBiologyMedicineInternal medicineCell biology

Abstract

fetched live from OpenAlex

Increasing amounts of evidence have indicated the important role of cancer stem cells (CSCs) in tumorigenesis and relapse. Metastasis is a key biological characteristic of malignant tumors. How cancer cells spread from the original tumor into the circulation and then infiltrate distant organs remains a topic of debate. Moreover, understanding the differences between metastasized and non-metastasized cancer cells is the key to develop strategies to block metastasis. In this review, we summarized the development of the CSC theory related to tumor metastasis over the last two decades.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.762
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.077
GPT teacher head0.424
Teacher spread0.347 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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