Suppression of Mouse Ependymoma Growth after Immunization with Tumor Ribosomal Complexes
Bibliographic record
Abstract
Immunization with ribosomal complexes, prepared from experimental ependymomas (transplanted in C57B/6J female mice) significantly decreases tumor growth and prolongs survival of hosts transplanted with this particular tumor. Experimental brain tumors present an interesting model for immunological studies because of the ‘priviledged’ situation of the brain itself, the lack of local lymphatic apparatus and the functional peculiarity of the blood-brain barrier. We studied a tumor model originally induced by methyl-cholanthrene and subsequently transplanted by Zimmerman and Arnold since 1940 [1]. The tumors grow either intracranially or subcutaneously in female mice of the inbred strain C57B/6J; their histopathology is considered stable. The immunogenicity of this tumor to the host has been demonstrated by Wilkins and Ketcham [2].
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".