Bibliographic record
Abstract
Bile acid (BA) metabolism was studied in the intestine, liver and plasma of rats at 0-1 day (neonates); 14 days (preweaning); 22 days (weaning) and 60 days (young adults) of age, as well as in the maternal tissues. In the intestine, total BA content (mumol/100 g body weight) decreased during neonatal life and reached maternal levels at 60 days. In the liver, BA increased up to 14 days and then decreased at 22 and 60 days of age, but these concentrations were higher than those found in the neonate and the mother. The serum concentrations in 14- and 22-day-old rats were more than 30 times higher than in the newborns. At 60 days, serum BA content was still twice that of the mother. BA composition in the intestine and the liver showed a reduction in 12 alpha-hydroxylated BA associated with an increase in chenodeoxycholic acid and 6 beta-hydroxylated BA during neonatal life. These data indicate an increased synthesis of chenodeoxycholic and 6 beta-hydroxylated BA after birth. It further suggests a possible defect in excretory mechanisms in neonatal life.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".