Proteinase‐activated receptors (PARs), platelets and angiogenesis
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Abstract With respect to the role of proteinase‐activated receptors (PARs), few cells have been as thoroughly studied as the platelet. PARs appear to act as the key receptors mediating the pro‐aggregatory and pro‐secretory effects of thrombin, but there is considerable variation from species to species in terms of which PARs are involved in these processes. In addition to contributing to hemostasis, platelets are increasingly being viewed as important contributors to healing and to tumor growth. This can be attributed to the many pro‐ and anti‐angiogenic factors that are stored within platelets and are released as sites of injury and new vessel growth. There is emerging evidence for an important role for PARs in regulating the release of growth factors from platelets, raising the specter that PARs may be a rational target for new therapies that will modulate repair processes and tumour growth. Drug Dev. Res. 59:395–399, 2003. © 2003 Wiley‐Liss, Inc.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it