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Record W2067236947 · doi:10.5539/cis.v6n1p133

The Hybrid Method of Fuzzy Feed-Forward Neural Network for Predicting Protein Secondary Structure

2013· article· en· W2067236947 on OpenAlexvenueno aff
Sania Vahedian Movahed

Bibliographic record

VenueComputer and Information Science · 2013
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicProtein Structure and Dynamics
Canadian institutionsnot available
Fundersnot available
KeywordsComputer scienceArtificial neural networkProtein secondary structureArtificial intelligenceData miningProtein structure predictionFuzzy logicSet (abstract data type)Neuro-fuzzyMachine learningFeedforward neural networkPattern recognition (psychology)Protein structureAlgorithmFuzzy control systemBiology

Abstract

fetched live from OpenAlex

With respect to the fact that the prediction of Protein secondary structure based on amino acids is very important, therefore, this study tries to present a new method based on the fuzzy combinational structure of a set of feed-forward neural networks so that the prediction accuracy of Protein secondary structure can be improved compared with the existing methods. Neural networks used in this paper are based on time windows; also, different methods have been established and trained to infer the three states of alpha- helix, beta- sheet and coils from DSSP results, and finally, combining the results of the abovementioned networks in a fuzzy manner, the prediction method of Protein secondary structure based on neural network has been improved. It should be noted that in this paper, CB513 and RS126 data sets which are valid data sets in evaluating prediction methods of Protein secondary structure known in research studies in this area have been used to train and evaluate the proposed method.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.006
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.231
Teacher spread0.227 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes1
Has abstractyes

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