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Record W2067880027 · doi:10.1159/000018403

Diluted Steroid Facial Wet Wraps for Childhood Atopic Eczema

2000· letter· en· W2067880027 on OpenAlexaboutno aff
Wenjing Tang

Bibliographic record

VenueDermatology · 2000
Typeletter
Languageen
FieldMedicine
TopicDermatology and Skin Diseases
Canadian institutionsnot available
Fundersnot available
KeywordsDermatologyAtopic dermatitisMedicineTopical steroidSteroidEndocrinologyHormone

Abstract

fetched live from OpenAlex

Recent epidemiological studies have suggested that atopic eczema (AE) is on the rise [1, 2]. Despite advances in the understanding of its immunopathogenesis, severe AE presents a management challenge to clinicians. In a small proportion of patients, the face can be the worst affected area and impose significant physical and psychological stress on schooling and daily activities. For children who have severe facial eczema and who are compliant, a short period of diluted steroid wet-wrap dressings on the face can often be helpful.The child is allowed to lie comfortably supine. Long scalp hair can be covered with a shower cap and the external auditory meati protected by cotton or plastic plugs to avoid inadvertent entry of water during treatment. The face is cleansed with warm water (about 25–30°C) and mopped dry. The dry parts of the forehead, central face, cheeks, chins, cutaneous lips and ear auricles are smeared with emollient, whereas a thin layer of a highly diluted steroid is applied onto the eczematous areas. The whole face and sometimes the upper neck, if also affected by eczema, are dressed with a double-layered wet gauze. The gauze sheets can be trimmed to fit individual regions and cuts made carefully to expose orifices (fig. 1). The next step is to apply a double-layered dry gauze on top of the wet gauzes. Adhesive tapes such as Micropore (3M Health Care, St. Paul, Minn., USA) can be used to secure various parts (fig. 2). This is further secured with Netelast (Seton Healthcare Group Plc, Oldham, UK), an elastic net bandage, and then with adhesive tapes at appropriate positions ending up as a facial mask (fig. 3). Size F of Netelast is most often used.In my experience, aqueous cream (formula: emulsifying wax 9%, white soft paraffin 15%, liquid paraffin 6%, phenoxyethanol 1%, add water to 100%) or emulsifying ointment (formula: white soft paraffin 50%, emulsifying wax 30%, liquid paraffin 20%) is used as emollient and diluent, and a new-generation topical corticosteroid such as 0.1% mometasone furoate (MF; 0.1% Elomet Ointment, Schering Canada Inc., Pointe Claire, Quebec, Canada) is used for treating the eczema. The preparation of a desired diluted topical steroid has been described elsewhere [3]. Briefly, aliquots of a steroid and a diluent are weighed using an electronic balance. Both components are dispensed in a single plastic medicinal box. Parents are instructed to mix them evenly when used and to use up the mixture within a short period of a few days to ensure stability of the mixture. Thus, a steroid to be diluted to 10% of its original concentration would mean one part of steroid added to nine parts of diluent. For base compatibility, a steroid cream is to be mixed with aqueous cream and a steroid ointment with emulsifying ointment. For wet-wrap dressings of the face, a 1-in-10 dilution of 0.1% MF cream or ointment is often used. However, depending on clinical situations, steroids of different dilutions can also be employed.The facial mask is usually kept for 2–3 h. Upon removal of the dressings, erythema and scaling would often have lessened. Open application of emollient can then be continued on a demand basis for the rest of the day. If in need, the procedure can be repeated once a day. In some patients where skin dryness dominates the clinical picture, plain emollient-only wet wraps can be used to reduce the skin dryness after their inflamed eczematous components have been controlled with diluted steroid wet wraps. Occasionally, patients may find the gauze sheets rough to the touch. In this case, a softer gauze with looser weaving such as Kerlix (A to Z Surgical Inc., San Jose, Calif., USA) could be used [4]. But Kerlix is not as easily available and cheap as the ordinary plain gauze sheets. Tubular dressings such as Tubifast (Seton Healthcare Group) can also be a comfortable and more convenient-to-apply alternative to plain gauze sheets but are more costly.Previous studies have shown that dilutes steroid wet wraps were beneficial for managing severe AE [3, 4, 5, 6, 7, 8, 9, 10]including a facial flare [4]. It is thought that the wet-wraps dressings enhance steroid penetrance, hydrate the stratum corneum and serve as a physical barrier against excessive scratching. However, occlusion also increases steroid absorption and the risk of local and systemic effects. Indeed, perioral dermatitis and adverse effects on the eyes [11]are unique to the prolonged application of potent steroid on facial areas. MF is a new-generation moderately potent to potent topical steroid having a high epidermal binding with minimal systemic absorption [12]. Hence the increased percutaneous steroid absorption consequent to occlusion and hydration can be reduced. In addition, MF has a very low risk of contact sensitization [13]. Facial wet wraps are useful for combating a flare of facial eczema. In the past year, 10 patients with flares of their facial eczema were given the treatment. They included 6 male and 4 female patients with a mean age of 8.4 years (range = 4–15 years) and long duration (mean = 7.15 years, range = 4–14 years) of childhood AE. All patients and their parents had preceding experience of using diluted steroid wet-wrap dressings for the four limbs and/or the body. For treating facial eczema, an intermittent regime of a 2- to 3-hour wrapping once a day for a few consecutive days was used. All parents reported good response and no significant clinical cutaneous signs of steroid side-effects were noted.However, to my current opinion, steroid wet wraps are most suitable for dry eczematous lesions. In cases of grossly exudative or infected eczema, wraps should best be withheld to avoid predisposing or exacerbating skin infections, and a short course of antibiotic and open application of steroid cream with or without topical antimicrobials is more desirable and preferred. Recently, Abeck et al. [9]have treated 6 patients with acute exacerbated atopic exzema using wet wraps with emollient-antiseptic preparations without steroids and achieved clinical improvement and reduction of Staphylococcus aureus colonisation. Such modification can therefore be more appropriate than using diluted steroid for weepy and excoriated eczema. The facial dressing procedure may scare some young children and babies. Therefore, before commencing treatment, careful explanation on the procedure should be given to parents and patients, and demonstration by a nurse could be very helpful to the parents who will carry out the treatment. All in all, with supervision and proper use on selected cases, diluted steroid facial wet wraps are as safe and effective as wet wraps used for elsewhere, and patients will find the procedure well tolerable.The author expresses sincere thanks to Miss Lisa Wong and her nurse colleagues for their participation in the demonstration of the wet-wrap technique, parental supervision and patient education.

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How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.014
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.258
Teacher spread0.245 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations11
Published2000
Admission routes1
Has abstractyes

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