MétaCan
Menu
Back to cohort
Record W2068120166 · doi:10.1159/000192905

On the Course of Carbon Monoxide Uptake and Release

2009· article· en· W2068120166 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueRespiration · 2009
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicHeme Oxygenase-1 and Carbon Monoxide
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsCarbon monoxideCarboxyhemoglobinMedicineBlood volumeMonoxideCarbon monoxide poisoningBreathingAnesthesiaPoison controlBiochemistryChemistryMedical emergencyInorganic chemistry

Abstract

fetched live from OpenAlex

The time course of carbon monoxide exchange has been predicted, using an improved computer model with well and poorly perfused body compartments. The model gives a good description of the time course of early uptake (2–6 min following a 40-ml dose of carbon monoxide). The half-time of subsequent elimination (4h breathing air) is also realistic. However, the early fall of blood carboxyhaemoglobin level (0–30 min post-exposure) proceeds more rapidly than the model would indicate. Possibly, carbon monoxide is at this stage equilibrating with sequestrated red cells or extravascular pigments. The simple rebreathing method offers a safe and convenient experimental method of administering carbon monoxide, and yields a good rapid estimate of total blood volume.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score0.197

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.244
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it