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Record W2068143304 · doi:10.1002/stem.602

Concise Review: Making a Retina—From the Building Blocks to Clinical Applications

2011· review· en· W2068143304 on OpenAlexafffund
Valerie A. Wallace

Bibliographic record

VenueStem Cells · 2011
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRetinal Development and Disorders
Canadian institutionsOttawa HospitalUniversity of Ottawa
FundersCanadian Institutes of Health ResearchStem Cell NetworkFoundation Fighting Blindness
KeywordsBiologyRetinaNeurogenesisNeuroscienceRetinalNeural stem cellNeural developmentCentral nervous systemStem cellCell biologyGenetics

Abstract

fetched live from OpenAlex

The retina is the neural tissue located at the back of the eye that captures and processes light and transmits this information to visual processing centers in the brain, which enables us to see. Basic research in retinal development has provided important insight on the control of cell fate, proliferation, and neurogenesis in the central nervous system. This review summarizes the major cellular and molecular events that occur during retinal development and highlights how this knowledge may be harnessed for new therapeutic strategies to treat retinal disease.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.004
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.002
Science and technology studies0.0000.001
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0040.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.066
GPT teacher head0.376
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations54
Published2011
Admission routes2
Has abstractyes

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