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Record W2068294067 · doi:10.1097/mcd.0b013e3282f4a10e

Localized acalvaria with craniosynostosis

2008· article· en· W2068294067 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueClinical Dysmorphology · 2008
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCraniofacial Disorders and Treatments
Canadian institutionsUniversity of British ColumbiaBC Children's Hospital
Fundersnot available
KeywordsMedicineCraniosynostosisSkullPresentation (obstetrics)AnatomyCraniosynostosesPathologyRadiology

Abstract

fetched live from OpenAlex

The authors report here a 3-year-old boy with localized absence of calvarial bones (partial acalvaria/hypocalvaria), associated with unique sagittal calcified bone and craniosynostosis. This major skull deformation led to a prominent protrusion of the cerebral hemisphere and other significant parenchymal changes that were well demonstrated by neuro-imaging. No digital abnormalities and only minor facial dysmorphism were observed; however, his development is grossly delayed. History and detailed investigations failed to explain the cause of his condition. Mutation testing of fibroblast growth factor receptor (FGFR) 1, 2 and 3 gave normal results. The combination of craniosynostosis and acalvaria in this surviving boy could be a rare presentation of a more lethal condition.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.266
Threshold uncertainty score0.574

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.312
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it