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Record W2069060962 · doi:10.1159/000120529

A Critical Appraisal of the Role of Brachytherapy for Pediatric Brain Tumors

2008· review· en· W2069060962 on OpenAlexaff
Mark Bernstein, Normand Laperrière

Bibliographic record

VenuePediatric Neurosurgery · 2008
Typereview
Languageen
FieldMedicine
TopicGlioma Diagnosis and Treatment
Canadian institutionsToronto Western Hospital
Fundersnot available
KeywordsBrachytherapyMedicineAstrocytomaRadiation therapyRadiologyCraniopharyngiomaSurgeryGlioma

Abstract

fetched live from OpenAlex

While brachytherapy is increasingly being utilized in adult patients with brain tumors, there has been very little experience with this approach in pediatric patients. This report reviews the current published experience with brachytherapy for brain tumors in children. Intracavitary irradiation with radioactive colloid is quite effective in controlling cystic craniopharyngiomas and represents an alternative approach to this subgroup of patients with craniopharyngiomas. There has been a substantial experience with the use of permanent interstitial implants in cases of low-grade astrocytoma in Europe, but its value is difficult to judge because of the variable natural history of these slow-growing neoplasms. Very few high-grade astrocytomas have been treated with brachytherapy in children, but children with localized recurrences after conventional therapy should be considered for this approach.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.931
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.003
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.338
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2008
Admission routes1
Has abstractyes

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