Esophagitis and anticonvulsant hypersensitivity syndrome
Bibliographic record
Abstract
Figure 1 Anticonvulsant hypersensitivity syndrome (AHS) is a rare syndrome caused by a severe idiosyncratic reaction to antiepileptic agents. A 61-year-old man developed cutaneous rash, fever, and dysphagia after 1 month of carbamazepine treatment for neuralgia. At endoscopy, starting from the upper esophagus, the mucosa was found to be fragile and covered with longitudinal, whitish, removable membranes with minimal oozing. Figure 2 Esophageal histology and brushing excluded cytomegalovirus infection and revealed significant eosinophilic infiltration. Carbamazepine was withdrawn, and treatment with oral steroids and antihistamine was started. Shortly afterwards, the fever subsided and the skin rash and dysphagia disappeared. Figure 3 Three weeks later, endoscopy showed complete healing of the esophageal mucosa, with persistent esophageal rings. The mucosal histology documented a decrease in eosinophils. In addition to hepatitis and colitis, esophagitis can also be a gastrointestinal manifestation of anticonvulsant hypersensitivity syndrome.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.010 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".