Cover Picture: Stereoselective Glycosylations Using (<i>R</i>)‐ or (<i>S</i>)‐(Ethoxycarbonyl)benzyl Chiral Auxiliaries at C‐2 of Glycopyranosyl Donors (Eur. J. Org. Chem. 22/2006)
Bibliographic record
Abstract
Abstract The cover picture shows the proposed mechanistic pathway for the stereoselective glycosylation based on Density Functional Theory calculations of the model compound. The protected sugar that has a chiral protecting group that is derived from mandelic acid and is attached to O‐2 after activation to an oxacarbenium ion species can form energetically favorable 6‐membered‐ring dioxolenium ions. The favored dioxolenium ion has the phenyl substituent in an equatorial position in both cases, allowing for the chirality of the protecting group to be transferred to the stereochemistry of the synthetically isolated glycoside. Details are discussed in the article by D. Whitfield, G.‐J. Boons et al. on p. 5007 ff.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.208 | 0.026 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".