Lithium Substitution Analysis of Na and K Phases in a Small Artery
Bibliographic record
Abstract
Cell Na in the rat tail artery was measured by replacing all extracellular Na with Li at 2°C. Water was partitioned with 14C-sorbitol as the marker. The binding capacity of the cytoplasm was estimated by ion-exchange after the destruction of cell membranes by alternate freezing and thawing. Cell Na is of the order of 20–25 mEq/kg dry weight and about 2/3 of this may be in free solution with [Na]i in the range of 15 mEq/liter. Cell K is about 220 mEq/kg dry weight and, of this, 30 mEq or more is bound so that [K]i is not greater than 190 mEq/liter. These estimates allow only for the low figure of 30 mEq as the sum of site-bound cell monovalent cations. It is shown, however, that as much as 50-60 mEq may be site-bound or otherwise restricted within the cell. A similar amount, mostly Na+, is site-bound within the paracellular matrix.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".