Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Two amide penicillins, 2-[(3,3-dimethyl-7-oxo-6-[2-phenylacetamido]-4-thia-1-azabicyclo[3.2.0]hept-2-yl)carbonyl]-1,2-benzisothiazol-3(2H)-one 1,1-dioxide (Wy-12,556) and 2-[2,3-dimethyl-7-oxo-6(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-ylcarbonyl]-1,2-benzisothiazol-3(2H)-one 1,1-dioxide, hydrate (Wy-12,405), were compared with benzathine penicillin G for their duration of therapeutic activity in mice; potassium penicillin G and potassium penicillin V were also included in this study. In animals primed with these agents the amide penicillins were significantly more active than benzathine penicillin G with respect to dosage. Wy-12,405 reached its peak of effectiveness in animals treated 4 days prior to infection. Wy-12,556 was two times more effective than Wy-12,405 in mice treated 8, 12 and 16 days prior to challenge. Although the potency ratios of the amide penicillins declined gradually after the 8th day, both continued to be more effective than benzathine penicillin G. When the treated mice were challenged with progressively larger numbers of bacterial cells Wy-12,556 proved to be more effective than benzathine penicillin G in combating the infection.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it