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Record W2069890343 · doi:10.2135/cropsci2001.413739x

Improving Erucic Acid Content in Rapeseed through Biotechnology: What Can the <i>Arabidopsis FAE1</i> and the Yeast <i>SLC1‐1</i> Genes Contribute?<sup>1,</sup><sup>2</sup>

2001· article· en· W2069890343 on OpenAlexaffabout
Vesna Katavić, Winnie Friesen, Dennis L. Barton, Kalie K. Gossen, E. Michael Giblin, Tammy Luciw, Jing An, Jitao Zou, S. L. MacKenzie, Wilfred A. Keller, Daryl Males, David C. Taylor

Bibliographic record

VenueCrop Science · 2001
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicLipid metabolism and biosynthesis
Canadian institutionsPlant Biotechnology InstituteUniversity of Saskatchewan
Fundersnot available
KeywordsErucic acidRapeseedBrassicaArabidopsisBiologyFatty acidBiochemistryTransgeneYeastGenetically modified cropsArabidopsis thalianaFood scienceBiotechnologyGeneMutantBotany

Abstract

fetched live from OpenAlex

The main goal of our research is to produce, by genetic manipulation, Brassica napus L. cultivars with higher amounts of 22:1 in their seed oil than in present Canadian high erucic acid rapeseed (HEAR) cultivars developed through traditional breeding, ideally with proportions of 22:1 approaching 80 mol% (828 g kg −1 ). To probe some rate‐limiting steps in the accumulation of triacylglycerols containing very long chain fatty acids (VLCFAs), particularly erucic acid (22:1), we have taken a transgenic approach, studying the effect of expressing two target genes in HEAR B. napus cv. Hero. To study the role of the elongase complex, involved in elongation of C 18 fatty acid moieties to produce VLCFAs, we expressed the Arabidopsis thaliana L., fatty acid elongase 1 ( FAE1 ) gene under the control of a seed‐specific promoter (napin), in Hero. This resulted in increased proportions of 22:1 in the seed oil, rising from 430 g kg −1 in non‐transformed controls to 480 to 530 g kg −1 22:1 in FAE1 transgenic Hero lines. The FAE1 lines exhibited higher elongase activity in vitro compared to control lines. These data suggest that the level of active condensing enzyme in the native elongase complex is somewhat rate limiting for synthesis of erucic acid and other VLCFAs in HEAR. In small scale field trials, the VLCFA and 22:1 content of FAE1 transgenic lines were superior to field‐grown control lines. We report that in field plot trials, the progeny of our best T 4 B. napus cv. Hero SLC1‐1 transgenic lines clearly out‐performed controls in terms of 22:1, oil content, and yield.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.075
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.004
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.224
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations52
Published2001
Admission routes2
Has abstractyes

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