Thermolability of Alkaline Phosphatase in the Evaluation of Renal Osteodystrophy
Bibliographic record
Abstract
Serum-alkaline phosphatase in man is mainly derived from bone or liver. It has been confirmed that alkaline phosphatase of skeletal origin is heat-labile. Normal individuals have mean heat-stable values of 30.7%. In children, healing fractures, and patients with osteitis fibrosa the alkaline phosphatase of bone origin is increased, and in these groups the mean thermostable values were 9.6, 21.8 and 18.7%, respectively. In these cases the decrease in thermostable values appear to be diagnostic even in the presence of a normal total alkaline-phosphatase value. From this study, thermostable alkaline phosphatase appears to be useful in the evaluation of osteitis fibrosa in patients with chronic renal failure both in cases with normal or elevated total alkaline-phosphatase values.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.019 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.002 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".