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Record W2070027337 · doi:10.1051/ata:2005008

Utilisation de la cotinine contenue dans les cheveux comme marqueur d'une exposition à la fumée de tabac. Méta-analyse d'études internationales

2005· article· fr· W2070027337 on OpenAlexaff
Ana Florescu, Gideon Koren, Julia Klein, Joey Gareri

Bibliographic record

VenueAnnales de Toxicologie Analytique · 2005
Typearticle
Languagefr
FieldMedicine
TopicSmoking Behavior and Cessation
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsCotinineGynecologyMedicineNicotine

Abstract

fetched live from OpenAlex

Au cours des 12 dernières années, nous avons établi et validé l'utilisation de la cotinine contenue dans les cheveux comme marqueur de l'exposition à la fumée de tabac. Cette méta-analyse, réalisée à partir de toutes les études disponibles de notre laboratoire et d'autres centres, est destinée à établir des valeurs de cotinine dans les cheveux, dans le contexte de l'exposition f à la fumée de tabac environnante. Les valeurs ci-dessous ont été mesurées sur plus de 1000 patients : Femmes non enceintes : Fumeuses actives cotinine (ng/mg) = 2.72 et [95% IC] = 2.32-3.13 Fumeuses passives cotinine (ng/mg) = 0.62 et [95% IC] = 0.51-0.74 Non exposées cotinine (ng/mg) = 0.29 et [95% IC] = 0.23-0.36 Femmes enceintes : Fumeuses actives cotinine (ng/mg) = 1. 7 et [95% IC] = 1.46-1.94 Fumeuses passives cotinine (ng/mg) = 0.07 et [95% IC] = 0-0.09 Non exposées cotinine (ng/mg) = 0.08 et [95% IC] = 0-0.09 Enfants : Passifs cotinine (ng/mg) = 0.96 et [95% IC] = 0.86-1.07 Non exposés cotinine (ng/mg) = 0.33 et [95% IC] = 0.25-0.4 Nouveau-nés : Exposés in utéro cotinine (ng/mg) = 1.42 et [95% IC] = 1.18-1.65 La séparation entre les différents états d'exposition avec un intervalle de confiance à 95% devrait pouvoir faciliter les recherches, ainsi que les cas cliniques où une exposition passive peut être dangereuse (par exemple des enfants avec de l'asthme vivant dans une maison de fumeurs) et aider l'assurance maladie.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.025
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (broad)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.994
Threshold uncertainty score0.065

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0120.025
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0060.020
Bibliometrics0.0020.003
Science and technology studies0.0010.001
Scholarly communication0.0030.001
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.117
GPT teacher head0.394
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2005
Admission routes1
Has abstractyes

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