A dominant mutation reveals asymmetry in MP/ARF5 function along the adaxial-abaxial axis of shoot lateral organs
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Bibliographic record
Abstract
The establishment of adaxial-abaxial polarity in plant lateral organs involves elaborate interactions between members of several transcription factor families, including the Auxin Response Factors (ARFs). We previously described a dominant allele of ARF5/MONOPTEROS (MP), termed MPΔ, which causes severe vascular hypertrophy in shoot lateral organs. Here we report that these organs are also disrupted in adaxial-abaxial polarity. Other MPΔ lateral organs with decreased vasculature show similar disruptions, suggesting that MP impinges on organ polarity through pathways separate from its role in promoting vascularization. Furthermore, we demonstrate that MPΔ exhibits an adaxial-abaxial asymmetry in its ability to influence organ development. Since ARFs previously implicated in polarity establishment function as transcriptional repressors, the transcriptional activator MP represents a novel link between auxin signal transduction and adaxial-abaxial polarity.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it