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Record W2074445110 · doi:10.1159/000136275

Metabolic Requirements for the Uptake of Noradrenaline by Isolated Atria and Vas Deferens of the Rabbit

2008· article· en· W2074445110 on OpenAlexaff
David M. Paton

Bibliographic record

VenuePharmacology · 2008
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMetabolism and Genetic Disorders
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsVas deferensRabbit (cipher)Internal medicineEndocrinologyHeart atriumChemistryPharmacologyCardiologyMedicineComputer science

Abstract

fetched live from OpenAlex

The metabolic requirements for the accumulation of (3H)-noradrenaline by rabbit atria and vas deferens have been studied. It was found that inhibition of either glycolysis or oxidation via the Krebs cycle alone had little effect on amine accumulation but inhibition of both processes greatly reduced accumulation of (3H)-noradrenaline by both tissues. Glycolysis was inhibited by iodoacetate and 2-deoxy-D-glucose. D-Glucose, D-mannose, pyruvate, lactate, oxaloacetate and β-hydroxy-butyrate could be utilised for the energy requirements of amine transport but D-galactose, D-fructose, 2-deoxy-D-glucose, 3-O-methyl-glucose and succinate were not.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.232
Threshold uncertainty score0.265

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.288
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations19
Published2008
Admission routes1
Has abstractyes

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